If you have large amounts of data one solution and cheap could be the following.
Using Norton Ghost...
It can image the whole drive, and write it to a CDR over multiple disks.
This would only be an option if you dedicated 1 drive for backup ?
Another app flying around is Backup Plus.
Very simular to MS Backup but it needs no user intervention once it is set up

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\' /> Not sure if it supports backing up to CDR.